Get Anesthesia and the Cardiovascular System: Annual Utah PDF

By Dennis T. Mangano M.D., Ph.D (auth.), Theodore H. Stanley MD, W. Clayton Petty MD (eds.)

ISBN-10: 0898385598

ISBN-13: 9780898385595

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ISBN-13: 9780898385663

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ISBN-13: 9780898385717

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ISBN-13: 9780898386028

ISBN-10: 9400956681

ISBN-13: 9789400956681

ISBN-10: 9401090017

ISBN-13: 9789401090018

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Extra resources for Anesthesia and the Cardiovascular System: Annual Utah postgraduate course in anesthesiology 1984

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1). Table II COMPARISON CARDIOVASCULAR EFFECTS Ca++ BLOCKERS Verapamil Nifedipine Diltiazem Systemic Vasodilation + A-V Conduction Slowing ++ Negative Inotropism + Heart Rate + ++ + + + Where + = an effect ·and - = no effect and + effect, and ++ = greater effect than +. + = little or no Calcium Antagonists and Anesthetic Drugs There are a large number of potential uses for calcium antagonists in the perioperative period) These include treatment of supraventricular arrhythmias, coronary and cerebral arterial spasm, hypertension, myocardial protection, uterine relaxation, and elective hypotension.

Of importance in this scheme are the steps from the biosynthesis of dopamine to vani 11 yl mandel i c ad d that may i nfl uence the anesthet i c management. The sympathetic nerve terminal is the primary store of norepinephrine where stimul ation of the sympathetic nervous system rel eases norepinephrine while catecholamine release from the adrenal medulla consists of 20% norepinephrine and 80% epinephrine. This ratio tends to reverse when an adrenal medullary tumor exists. 23 Table 2. Substrate Biosynthesis of Catecholamines Enzyme Enzyme Inhibitors Phenyl al ani ne t .

The mismanagement or denial of insulin administration can lead to severe postoperative metabolic derangement which may be difficult to correct and may jeopardize survival. The stress response - metabolic changes During stress, substrates are mobilised from storage sites and other tissues and redistributed to central organs. These metabol ic changes are mediated by the stress hormones especially the catecholamines, cortisol and glucagon. l Glucose production is increased due mainly to hepatic glycogenolysis and gluconeogenesis.

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Anesthesia and the Cardiovascular System: Annual Utah postgraduate course in anesthesiology 1984 by Dennis T. Mangano M.D., Ph.D (auth.), Theodore H. Stanley MD, W. Clayton Petty MD (eds.)


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