Download PDF by Icon Health Publications: Ascites - A Medical Dictionary, Bibliography, and Annotated

By Icon Health Publications

ISBN-10: 0497000989

ISBN-13: 9780497000981

ISBN-10: 1417541482

ISBN-13: 9781417541485

It is a 3-in-1 reference ebook. It supplies a whole scientific dictionary masking thousands of phrases and expressions with regards to ascites. It additionally offers wide lists of bibliographic citations. ultimately, it offers details to clients on easy methods to replace their wisdom utilizing a variety of web assets. The e-book is designed for physicians, scientific scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to familiarize yourself with study devoted to ascites. in case your time is efficacious, this ebook is for you. First, you won't waste time looking the net whereas lacking loads of appropriate details. moment, the publication additionally saves you time indexing and defining entries. ultimately, you won't waste time and cash printing 1000's of websites.

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Extra resources for Ascites - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Sample text

This information will have the potential to improve the efficacy of several drugs, as many have limited water solubility and exhibit toxicity related to formulation, and ultimately provide safer treatments to cancer patients. In addition novel insights will be gained by completion of the comparitive studies in debulked and nondebulked animals related to the effects of adhesions on treatment outcomes and drug pharmacokinetics and disposition. These studies will assess the potential of nanoparticulate paclitaxel delivered intraperitoneally as a means to improve on the current treatment of women with ovarian cancer.

In Aim 1, we will examine how DA D2 receptor, a G-protein coupled receptor (GPCR), Studies 29 can influence VEGFR-2 signaling pathways. By utilizing genetic and pharmacological approaches, Aim 2 will focus to reveal how peripheral DA might affect normal and pathological angiogenesis mediated by VPF/NEGF. In Aim 3, investigation will be carried out to define the role of DA and its related molecules as anti-angiogenic agents in both tumor ascites as well as solid tumor models. Moreover, we will examine whether DA or related compounds can be employed with other conventional drugs (such as Taxol) in preclinical settings.

Molecular genetic and pharmacological manipulation of these pathways will allow us to evaluate the potential for therapies that target LPA metabolism in treatment of ovarian cancer. Successful completion of the research will provide the framework and impetus to develop novel effective therapeutics for ovarian cancer. ; Associate Professor; Medicine; University of Pittsburgh at Pittsburgh 350 Thackeray Hall Pittsburgh, Pa 15260 Timing: Fiscal Year 2002; Project Start 01-APR-2001; Project End 31-MAR-2005 Summary: (applicant's description): MUC1 is a well characterized marker for many cancers of epithelial origin that also directly contributes to the aggressive metastatic phenotype of tumors.

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Ascites - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications


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